BACKGROUND:

Vesicourethral anastomotic stricture is an important medium-term and long-term complication of radical prostatectomy and its incidence and causality are heterogeneous.

OBJECTIVES:

To analyze and determine the causes related to vesicourethral anastomotic stricture, including patient characteristics and preoperative, intraoperative, and postoperative factors.

MATERIALS AND METHODS:

A retrospective case-control study was conducted that reviewed the case records of patients admitted to the Urology Service of the Hospital Juárez de México within the time frame of 2010 to 2016 that were diagnosed with prostate cancer and underwent video-endoscopic extraperitoneal radical prostatectomy. For the statistical analysis, the relative risk was calculated, and the chi-square test and Student’s t test were performed.

RESULTS:

Seventy-four patients were registered. Thirty-one of them were diagnosed with vesicourethral anastomotic stricture during their minimum 3-year follow-up period. Risk factors were diabetes mellitus (p = 0.003), anastomotic interrupted suture technique (p = 0.03), lower prostate volume (53 g) (p = 0.02), and postoperative radiotherapy (p = 0.001).

CONCLUSIONS:

The incidence of vesicourethral anastomotic stricture was high. Diabetes mellitus, the use of interrupted sutures in the anastomosis, adjuvant radiotherapy, and lower prostate volume (53 g) had a statistically significant relation to the presence of stricture.