SciELO - Scientific Electronic Library Online

 
vol.78 issue5Frequency of allelic variants of the TMPRSS2 gene in a prostate cancer-free Southwestern Colombian population author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista mexicana de urología

On-line version ISSN 2007-4085Print version ISSN 0185-4542

Abstract

GURROLA-ORTEGA, Ángel et al. Testicular cancer: Incidence, epidemiology and etiology. Five years of experience at the Hospital General de México Dr. Eduardo Liceaga. Rev. mex. urol. [online]. 2018, vol.78, n.5, pp.347-353.  Epub June 25, 2021. ISSN 2007-4085.  https://doi.org/10.24245/revmexurol.v78i5.2408.

BACKGROUND:

Testicular cancer accounts for 5% of the tumors in reproductive-age men and there has recently been an increase in its incidence. Diagnosis is made through clinical evaluation, tumor markers, and testicular ultrasound. Histologic strain determines treatment response and outcome.

OBJECTIVE:

To report the epidemiologic, histopathologic, and etiologic characteristics of testicular cancer at a tertiary care hospital within the time frame of 2012-2017.

MATERIALS AND METHODS:

A retrospective, observational, and descriptive study was conducted on patients with the diagnosis of testicular cancer of any histologic strain seen at the urology service of the Hospital General de México within the time frame of 2012 to 2017. The qualitative variables were expressed as simple, relative frequencies in percentages. Frequency variability was obtained through the 95% CI. Age was expressed in median and maximum and minimum values. The chi-square test and the Kruskal-Wallis test were employed to contrast the differences between tumor types, according to the variables analyzed.

RESULTS:

A total of 142 patients were studied, 44.4% of whom presented with mixed germ cell tumors and 43.7% with classic seminomas. Fifty percent of the patients presented with the disease at 20 to 30 years of age (mean 35.5). With respect to laterality, 56.3% of the tumors were on the left side and 43.7% on the right. In relation to lymph node dissemination (N) of the seminomatous tumors, 80.6% of the cases (n = 50) were stage N0 and 95.2% (n = 59) did not present with pulmonary metastasis, or any other, at the time of diagnosis. Of the nonseminomatous tumors (mixed germ cell tumors), 57.2% (n = 36) were stage N0 and 87.3% (n = 55) were M0. There was a slight increase in testicular cancer in the last two years.

CONCLUSIONS:

Despite our results, we believe a different study methodology is required to determine the cause of testicular cancer in our population.

Keywords : Testicular cancer; Tumor markers; Mexico; Germ cell tumors; Seminomas; Seminomatous tumors.

        · abstract in Spanish     · text in Spanish