Abstract

ROMERO, César; OSTROSKY, Feggy  and  CAMARENA, Beatriz. Effect of Risk Alleles MAO-A and DRD4 on Aggression Measures. Acta de investigación psicol [online]. 2012, vol.2, n.1, pp.568-581. ISSN 2007-4719.

Among the factors associated with the predisposition to violent behavior is the bearing of risk alleles. To investigate the effect of two risk alleles (low activity of MAO-A and 7 repeat DRD4) 60 healthy men were assessed on psychological scales of aggression. The results indicated that both the main effect of each of the risk alleles, and their interaction impact on measures of hostility, anger, impulsivity, empathy and antisocial traits of psychopathy. We conclude that it is necessary to investigate the effect of these alleles on brain structure and function; these alleles apparently also confer risk for the development of violent behavior.

Keywords : Aggression; DRD4; Epistasis; Impulsivity; MAO-A; Violence.