Abstract

LOPEZ-ALMADA, Gabriela et al. Preventive Approach in Non-Alcoholic Fatty Liver Disease. Epistemus (Sonora) [online]. 2022, vol.16, n.32, 11.  Epub Sep 23, 2022. ISSN 2007-8196.  https://doi.org/10.36790/epistemus.v16i32.185.

Obesity is currently a worldwide public health problem. It is characterized by its negative impact on multiple organs, including the liver, through the development of diseases such as non-alcoholic fatty liver disease (NAFLD), which can promote the development of hepatocellular carcinoma. This review discusses the association between obesity and the development of NAFLD, emphasizing on the importance of a preventive and interventional approach during the early stages of the disease, as well as the potential effect of some dietary bioactive compounds. In this regard, it is advisable to focus the intervention on improving BMI, through a program of physical activity, nutritional and health education, and changes in dietary patterns. The inclusion of foods rich in bioactive compounds, such as phenolic compounds, fiber and vitamins can provide an antioxidant, anti-inflammatory and anti-obesogenic effect that could hinder the progression of NAFLD and other comorbidities and complication.

Keywords : obesity; public health; bioactive compounds; non-alcoholic fatty liver; preventive approach.