Abstract

BAUTISTA GARFIAS, Carlos Ramón et al. In vitro Activation of bovine monocytes with Lactobacillus casei: nitric oxide production. Ecosistemas y recur. agropecuarios [online]. 2016, vol.3, n.8, pp.237-242. ISSN 2007-901X.

This research was carried out with the objective of determine the production of nitric oxide (NO) from monocytes of bovine peripheral blood exposed in vitro to L. casei. The NO production was measured every 24 hours during of 4 d in monocyte cultures of bovine peripheral blood of 4 to 6 months of age (MOA) (n = 4), 8 MOA (n = 3), and 12 MOA (n = 8), exposed (E) or not exposed (NE) to Lactobacillus casei. On each of the 24 h periods, a significant production (p < 0.01) of NO was observed on the monocytes exposed in comparison with those not exposed. The difference was more clear on the monocytes of groups 4 and 6 MOA. The use of L. casei can be important in establishing stimulation measures for the innate immunity in bovines against diseases produced by various pathogens.

Keywords : Monocytes; bovine; in vitro activation.