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Cirugía y cirujanos

On-line version ISSN 2444-054XPrint version ISSN 0009-7411

Abstract

ARSLANOğLU, Tuğçe et al. Can platelet activation markers predict preeclampsia and/or its severity?. Cir. cir. [online]. 2024, vol.92, n.1, pp.52-58.  Epub May 07, 2024. ISSN 2444-054X.  https://doi.org/10.24875/ciru.23000226.

Objective:

This study aimed to evaluate the value of platelet activation markers in predicting preeclampsia and its severity. Preeclampsia is a serious pregnancy complication that affects 3-5% of pregnancies and can lead to significant morbidity and mortality for both the mother and the fetus.

Methods:

The study included 99 patients diagnosed with preeclampsia and 60 healthy pregnant women as a control group. Platelet activation markers such as mean platelet volume (MPV), platelet distribution width (PDW), platelet count, and plateletcrit were evaluated along with other clinical parameters.

Results:

The results of the study showed that platelet activation markers, particularly PDW and MPV, are valuable in the diagnosis and follow-up of preeclampsia. However, they are not sufficient to predict the severity of the disease.

Conclusion:

The study suggests that platelet activation markers could aid in predicting, diagnosing, and managing preeclampsia. However, further research is needed to determine the role of these markers in predicting the severity of the disease. The findings of this study could contribute to the development of more effective strategies for the prevention and management of preeclampsia, which could ultimately improve maternal and fetal outcomes.

Keywords : Mean platelet volume; Plateletcrit; Platelet activation markers; Preeclampsia.

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