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Medicina crítica (Colegio Mexicano de Medicina Crítica)
Print version ISSN 2448-8909
Abstract
SANCHEZ CALZADA, Armando et al. Mean platelet volume to rule out sepsis. Med. crít. (Col. Mex. Med. Crít.) [online]. 2016, vol.30, n.2, pp.87-94. Epub Aug 30, 2021. ISSN 2448-8909.
Sepsis is one of the main causes of admission to the intensive care unit, and a prompt treatment reduces mortality significantly. Inflammatory diseases, including sepsis, affect the mean platelet volume (MPV); the level appears to be correlated with the degree of inflammation.
Objective:
To determine the utility of MPV as a marker of bacterial infection.
Material and methods:
A prospective, longitudinal, descriptive, observational study. All patients admitted to the ABC Medical Center intensive care unit were included. Group 1: individuals diagnosed with sepsis; Group 2: those without sepsis.
Results:
MPV elevation was found above 7.4 fL in the sepsis group (p < 0.001), with better determination at 72 hours (p < 0.001). The VPM remained low in the group of patients without sepsis (p < 0.012).
Conclusions:
The VPM can be used as a marker of bacterial infection in centers where there are no such markers as procalcitonin.
Medical centers that have the tools to measure procalcitonin can increase their sensitivity and specificity of diagnosis of bacterial sepsis with the use of VPM.
The VPM is an inexpensive and easily accessible marker of bacterial infection.
Keywords : Mean platelet volume; sepsis; bacterial infection marker.
