Abstract

ALANIS-NARANJO, José Martín; VEGA-NAVA, Carlos Tzalam; ALANIS-NARANJO, María de Lourdes  and  BANUELOS-ALMADA, Erick Alexis. Myxedema coma associated with SARS-CoV-2 infection. Med. crít. (Col. Mex. Med. Crít.) [online]. 2022, vol.36, n.2, pp.116-120.  Epub Nov 18, 2022. ISSN 2448-8909.  https://doi.org/10.35366/104875.

Although SARS-CoV-2 infection is known to be an important cause of lung disease, multiple extrapulmonary manifestations associated with COVID-19 have been observed. There are reports of thyrotoxicosis secondary to COVID-19 in the literature, but cases of decompensated hypothyroidism due to COVID-19 are rare. We report the case of a 37-year-old female patient with obesity who presented myxedema coma associated with SARS-CoV-2 infection. The pro-inflammatory state secondary to obesity, direct damage to the thyroid gland by SARS-CoV-2, and the elevation of inflammatory mediators in the blood observed during viral infection could be mechanisms that trigger myxedema coma. In patients with severe COVID-19, the intentional search for signs of myxedema coma and its confirmation with a thyroid profile at hospital admission is important.

Keywords : Myxedema coma; COVID-19; SARS-CoV-2; Mexico.

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