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Medicina crítica (Colegio Mexicano de Medicina Crítica)
Print version ISSN 2448-8909
Abstract
AGUILAR ARCIGA, Themis Gwendolyne and ESTRADA GUTIERREZ, Alfonso. Evolution of patients with acute kidney injury secondary to obstetric complications treated with continuous renal replacement therapy. Med. crít. (Col. Mex. Med. Crít.) [online]. 2022, vol.36, n.5, pp.272-279. Epub June 02, 2023. ISSN 2448-8909. https://doi.org/10.35366/106508.
Introduction:
Acute kidney injury associated with pregnancy or obstetric complications (PR-AKI) is a disease that occurs due to multiple etiologies of which little has been studied, with an estimated mortality of 4.3%.
Objective:
To analyze the evolution of patients with acute kidney injury secondary to obstetric complications (PR-AKI) who received continuous renal replacement therapy (CRRT) in the Intensive Care Unit of the Hospital de la Mujer de Morelia, Michoacán.
Material and methods:
Retrospective, longitudinal, descriptive study. A review of the records of patients who required CRRT secondary to obstetric complications was carried out during January 2013-December 2019. The Student’s t test was applied, considering the statistically significant results if p < 0.05.
Results:
Thirteen patients who required CRRT were included. The mean age of the patients was 26.18 years. The CRRT criteria were: AKI grade 2 or 3 and RIFLE stage injury or failure and potassium ≥ 6.5 mEq/L; urea ≥ 150 mg/dL; urinary index ≤ 0.5 mL; pH < 7.10 and HCO3 ≤ 20 mEq/L; SCr ≥ 2.4 mg/dL; water overload > 10%; BUN > 30 mg/dL.
Conclusions:
The incidence of women requiring CRRT is 3.2 cases/100 obstetric complications. Ninety-two percent of the patients had recovery of renal function while the progression to chronic kidney disease dependent on other modalities of renal replacement therapy was 8%.
Keywords : Continuous renal replacement therapy; acute kidney injury; obstetric complication; preeclampsia; HELLP syndrome.