Abstract

ROSAS-SANCHEZ, Karina; GUTIERREZ-ZARATE, Damián; SEVERINO-LUGO, Hiram  and  SANTIAGO-GERMAN, David. Invasive mechanical ventilation in patients with COVID-19 in a private hospital in Mexico. A case series: description and evolution of an early intubation protocol. Med. crít. (Col. Mex. Med. Crít.) [online]. 2022, vol.36, n.5, pp.318-322.  Epub June 02, 2023. ISSN 2448-8909.  https://doi.org/10.35366/106514.

The mortality and ventilation strategies of COVID-19 ARDS vary in the literature. The objective of this case series is to describe the clinical course of patients on invasive mechanical ventilation with COVID-19 and its outcome at 28 days. Twenty-one patients were included with an average age of 49 ± 13 years, 81% male and 38% with at least one comorbidity. The initial ventilatory variables were PaO2/FiO2 of 135 ± 53, PEEP 12 cmH2O, plateau pressure 26 ± 4.8 cmH2O, static compliance 32 ± 8.5 mL/cmH2O, driving pressure 15 ± 3.9 cmH2O, and mechanical power 19.2 ± 4 J/min. 67% of the patients received prone position and in 76% a neuromuscular blocker was used. The 28-day outcomes were 21 days of mechanical ventilation-free days and 14% mortality.

Keywords : Mechanical ventilation; COVID-19; acute respiratory distress syndrome; critical ill patient.