Background:

Chronic spontaneous urticaria is a frequent disease that affects the quality of life of patients. Helicobacter pylori infection has increased in the world, linking current studies with a link between both entities.

Objective:

To determine the relationship between chronic urticaria and Helicobacter pylori infection.

Methods:

An observational cohort study was conducted with the objective of demonstrating the relationship between chronic urticaria and Helicobacter pylori infection in the allergology clinic of the Hospital Universitario “Manuel Ascunce Domenech” in the province of Camagüey, Cuba, in the period from January 2015 to December of 2016. A universe composed of 93 patients with spontaneous chronic urticaria and the sample by the 43 who met the criteria and formed the case and control group were the 35 apparently healthy patients who gave informed consent for the study.

Results:

76.6 % of the women had urticaria and the mean age was 36.10 years. The serological study was positive in 100 % of the cases.

Conclusions:

In the present study, the relationship between chronic urticaria and Helicobacter pylori infection was demonstrated. Apparently, the eradicating treatment for Helicobacter pylori was effective as the patients had no symptoms after treatment. Specific immunoglobulin G and urease test together constitute a suitable diagnostic module for the diagnosis of Helicobacter pylori conditions.