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Revista alergia México
On-line version ISSN 2448-9190
Abstract
ORTEGA-LOPEZ, María Claudia; VALDERRAMA-CISNEROS, Abel and SANABRIA-CRUZ, Angie. Autoimmune encephalitis-limbic encephalitis. A Clinical case. Rev. alerg. Méx. [online]. 2020, vol.67, n.3, pp.297-304. Epub June 02, 2021. ISSN 2448-9190. https://doi.org/10.29262/ram.v67i3.770.
Background:
Autoimmune encephalitis occurs as a subacute condition with a strong infectious association in children. In the last 20 years, the frequency of non-infectious cases has increased significantly.
Clinical case:
A previously healthy eight-year-old male child with normal neurodevelopment, without a history of consanguinity, manifested progressive neurological deterioration with autoimmune encephalitis-limbic encephalitis up to hypothalamic dysfunction.
Conclusion:
In the mentioned case, it was documented that an inborn error of the immune system generated a severe neurological clinical picture, with permanent and irreversible damage, secondary to lack of immunological memory in the broad clinical context of a common variable immunodeficiency.
Keywords : Neurological impairment; Inborn error of the immune system; Common variable immunodeficiency; Autoimmune encephalitis; Limbic encephalitis; Children.