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Revista médica del Hospital General de México
On-line version ISSN 2524-177XPrint version ISSN 0185-1063
Abstract
MIGDAN, Carmen M. and LERMA-PUERTAS, Diego. Perinatal morbidity in gestations with pathological combined first trimester screening for aneuploidies and normal karyotype. Rev. med. Hosp. Gen. Méx. [online]. 2022, vol.85, n.3, pp.114-119. Epub Oct 07, 2022. ISSN 2524-177X. https://doi.org/10.24875/hgmx.21000096.
Objective:
Positive Combined First Trimester Screening and by risk groups: 0-50, 51-100, 101-150, 151-200, 201-250, and normal karyotype relate with negative screening for adverse perinatal results.
Method:
Retrospective study of cases and controls in single pregnancies, with predictive analysis using multivariate logistic regression.
Results:
3,791 screenings were performed at our unit in 2012, with a screening/number of deliveries ratio of 89.9%. There is a greater likelihood of the newborn being underweight (AOR = 2.6, 95% CI 1.2 – 5.7), premature (OR = 2.2, 95% CI 1.03 – 4.5), admitted to the ICU (OR = 7.4, CI 95% 1.5 – 34.6) or admitted to the Neonates department (AOR = 8.1, 95% CI 1.7 – 37.7) in the case group.
Conclusion:
Combined first trimester screening is a predictive method for pregnant women with a higher risk of adverse perinatal outcomes.
Keywords : PAPP-A; β-HCG; Adverse perinatal outcomes; Aneuploidies.
