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Revista médica del Hospital General de México
On-line version ISSN 2524-177XPrint version ISSN 0185-1063
Abstract
TALLABS-VILLAFANA, Felipe de J. et al. Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos. Rev. med. Hosp. Gen. Méx. [online]. 2023, vol.86, n.1, pp.12-16. Epub June 12, 2023. ISSN 2524-177X. https://doi.org/10.24875/hgmx.22000059.
Purpose:
To describe the institutional experience of treatment with volumetric modulated arc therapy (VMAT) in prostate cancer in the Mexican population of the Regional Hospital "Centenario de la Revolución Mexicana", ISSSTE, Morelos.
Methods:
A retrospective study of patients with prostate cancer treated with radiotherapy with moderate hypofractionation at doses of 70.2Gy in 26 fractions was performed, between January 2017 and January 2021.
Results:
55 patients were included in the analysis, with a median follow-up of 20.7 months, biochemical control was 100%. Acute gastrointestinal toxicity grade 1 or less occurred in 87.3% of patients, grade 2: 9.1% y grade 3 in 3.6%; acute genitourinary toxicity grade 1 or less in 90.9%, grade 2: 7.3% and grade 3: 1.8%. Regarding chronic gastrointestinal toxicity grade 1 or less, it was 95.3%, grade 2: 4.8%, There have been no grade 3 or higher cases, chronic genitourinary toxicity grade 1 or less 90.5%, grade 2: 7.1%, grade 3: 2.4%.
Conclusions:
Moderate hypofractionation in prostate cancer in the Mexican population presents excellent biochemical control and an adequate toxicity profile.
Keywords : Hypofractionation; Cancer; Prostate; Mexico.