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Gaceta mexicana de oncología
On-line version ISSN 2565-005XPrint version ISSN 1665-9201
Abstract
SERRANO-OLVERA, Juan Alberto et al. Disseminated intravascular coagulation associated with metastatic gastric cancer: One case report and systematic literature review. Gac. mex. oncol. [online]. 2019, vol.18, suppl.1, pp.8-17. Epub Oct 17, 2022. ISSN 2565-005X. https://doi.org/10.24875/j.gamo.19000154.
Background:
Disseminated intravascular coagulation (DIC) and bone marrow metastases are infrequent in gastric cancer (GC) and confers a dismal prognosis.
Objective:
We present a case of metastatic GC associated with DIC. We conducted a systematic review of the literature on the chemotherapy efficacy in this scenery.
Reported case:
A 37-year-old woman with metastatic poorly differentiated gastric adenocarcinoma, and DIC, who was treated with 5-Fluorouracilo, ácido folínico, oxaliplatino (FOLFOX)..
Conclusions:
The presence of DIC in asoociation with metastatic GC is uncommon and imposes a decrease in survival as well as a therapeutic challenge. Chemotherapy shows efficacy in the control of GC and DIC compared to the best supportive care.
Keywords : Gastric cancer; Disseminated intravascular coagulation; Chemotherapy; Prognosis.