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Gaceta mexicana de oncología
On-line version ISSN 2565-005XPrint version ISSN 1665-9201
Abstract
RODRIGUEZ-AGUIRRE, Manuel I. et al. Clinical features and treatment outcome of children with acute lymphoblastic leukemia and hyperleukocytosis. Gac. mex. oncol. [online]. 2021, vol.20, suppl.1, pp.23-27. Epub Aug 22, 2022. ISSN 2565-005X. https://doi.org/10.24875/j.gamo.21000031.
Introduction:
Hyperleukocytosis in children with acute lymphoblastic leukemia (ALL) has been associated with early morbidity and mortality.
Clinical Case:
We analyzed clinical data from 6 patients with ALL. We documented adverse events within the first 28 days in patients with a white blood cell (WBC) count ≥100 × 10(9)/l and reviewed their management. The most frequent biochemical alterations were hyperuricemia and hyperglycemia There were no severe complications or deaths.
Conclusions:
With improved management, including supportive care, early mortality in patients with ALL and hyperleukocytosis could be decreased remarkably.
Keywords : Leukemias; Hypeleukocytosis; Medical treatment; Morbidity; Children.
