Abstract

MARTINEZ-RODRIGUEZ, Juliana et al. Clinical spectrum of a syndromic diagnosis: Lethal midline granuloma. Gac. mex. oncol. [online]. 2022, vol.21, suppl.1, pp.16-20.  Epub Sep 11, 2023. ISSN 2565-005X.  https://doi.org/10.24875/j.gamo.22000125.

A 73-year-old man presented to the emergency department for 2 months of erythema, warmth, and blushing on the tip of the nose, with progression to ulcerative and granulomatous tissue and posterior necrotizing compromise of the nasal septum, despite antibiotic schemes. A diagnosis of lethal midline granuloma was made, a disease with a wide spectrum of etiological diagnostic possibilities and usually a poor prognosis. A biopsy sample confirms a NK/T-cell lymphoma. The patient did not accept the proposed chemotherapeutic treatment. He requested voluntary discharge and later died.

Keywords : Extranodal NK-T-cell lymphoma; Lethal midline granuloma; Colombia.