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Revista mexicana de oftalmología
On-line version ISSN 2604-1227Print version ISSN 0187-4519
Abstract
RAMIREZ-PATINO, Lorena et al. Ocular brachytherapy in the treatment of retinoblastoma. Experience in the Hospital Infantil de México. Rev. mex. oftalmol [online]. 2019, vol.93, n.4, pp.194-199. Epub Aug 06, 2021. ISSN 2604-1227. https://doi.org/10.24875/rmo.m19000078.
Objective:
To describe results and complications of salvage eye treatment with brachytherapy in patients with diagnosis of bilateral retinoblastoma (Rb) and only one eye.
Methods:
Case series where we included all retinoblastoma patients treated with ocular brachytherapy with Iodine-125 at the Hospital Infantil de Mexico after failure of eye salvage with intravenous chemotherapy, focal transpupillary laser o transconjunctival cryotherapy and external beam radiotherapy.
Results:
We analyzed 7 patients, 2 females and 5 males. Two had hereditary retinoblastoma and all had bilateral disease. Mean follow-up after treatment was 5.35 years (range 3.3–11 years). Tumor control was achieved in five of seven patients; two patients undergone enucleation due to failure to achieve tumor control. One of the patients died because of secondary neoplasm.
Conclusions:
Ocular brachytherapy treatment in a tertiary care center offers possibilities of ocular preservation in patients with bilateral Rb and maximum oncological treatment.
Keywords : Retinoblastoma; Brachytherapy; Cancer; Acquired blindness; Salvage therapy.