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Revista mexicana de angiología
On-line version ISSN 2696-130XPrint version ISSN 0377-4740
Abstract
GONZALEZ-SOLIS, Luis D. et al. Arterial calcification of the medial layer in the foot and risk of major amputation in diabetic foot ulcers. Rev. mex. angiol. [online]. 2024, vol.52, n.1, pp.1-6. Epub Apr 16, 2024. ISSN 2696-130X. https://doi.org/10.24875/rma.24000001.
Background:
Medial arterial calcification (MAC) of the foot is a predictor of cardiovascular morbidity and mortality in diabetics. The MAC score is a tool to describe with plain radiographs the burden of inframalleolar arterial calcification.
Objective:
To determine the degree of association between MAC and the risk of major amputation.
Methods:
Retrospective longitudinal cohort study analyzing radiographs of extremities with diabetic foot from March 1, 2021 to July 31, 2022. They were classified according to their MAC score and interventions performed at 6 months were recorded; chi-square test and relative risk test were performed to determine significant association between severe MAC and major amputation.
Results:
Out of 102 extremities studied, 37 patients (35.9%) had severe MAC; 28 suffered major amputation, with a significant risk estimation (RR: 3.28, CI: 95% 1.985-5.428).
Conclusion:
Severe MAC in patients with diabetic foot increases 3.2 times the risk of a major amputation during the 6 months following the appearance of an ulcer.
Keywords : Diabetic foot; Ulcer; Amputation; Arterial calcification; Inframalleolar disease; Peripheral artery disease.
