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Boletín médico del Hospital Infantil de México
versión impresa ISSN 1665-1146
Resumen
TECO-CORTES, Javier A. y ARRECILLAS-ZAMORA, Myrna D.. Disseminated mucormycosis in a child with acute lymphoblastic leukemia: autopsy findings. Bol. Med. Hosp. Infant. Mex. [online]. 2023, vol.80, suppl.1, pp.1-6. Epub 11-Sep-2023. ISSN 1665-1146. https://doi.org/10.24875/bmhim.22000050.
Background:
Mucormycosis is a rare infection caused by ubiquitous fungi of the Mucorales order that mainly affects immunocompromised patients. These fungi have an important tropism for blood vessels that allows them to spread rapidly and cause thromboembolic events.
Case report:
We present a case of an 8-year-old male patient diagnosed with acute lymphoblastic leukemia treated with chemotherapy. He presented icteric syndrome, hepato-splenomegaly, and data of intestinal obstruction. Although he underwent intestinal resection, he did not improve and died. The autopsy identified disseminated mucormycosis involving the brain, lungs, esophagus, small intestine, colon, and pancreas.
Conclusions:
Hematological neoplastic diseases and their treatment are important risk factors for developing infections by opportunistic microorganisms such as mucormycosis. Early diagnosis and adequate treatment are essential due to their intrinsic difficulty and the high mortality rate of these cases.
Palabras llave : Lymphoblastic leukemia; Mucormycosis; Neutropenia; Autopsy; Amphotericin B.