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Cirugía y cirujanos
versión On-line ISSN 2444-054Xversión impresa ISSN 0009-7411
Resumen
DURAN-POVEDA, Manuel et al. Adequacy of antibiotic prophylaxis protocol in appendectomies in children. Cir. cir. [online]. 2019, vol.87, n.4, pp.410-415. Epub 29-Nov-2021. ISSN 2444-054X. https://doi.org/10.24875/ciru.19000663.
Objective:
To assess compliance of antibiotic prophylaxis in surgery for acute appendicitis in children and its effect on surgical site infection.
Methods:
We carried out a prospective cohort study to evaluate compliance of antibiotic prophylaxis in appendectomies in children. An assessment of the level of compliance with prophylaxis was made, as well as the causes of non-compliance. The effect of non-compliance of antibiotic prophylaxis on the incidence of surgical site infection was studied with the adjusted relative risk (RR) with a backstep logistic regression model.
Results:
The study included a total of 412 patients. Antibiotic prophylaxis was indicated in 348 patients, and administered in 95.7% of cases, with an overall protocol compliance of 90.7%. The principal cause of non-compliance was time of initiation. Cumulative incidence of surgical site infection was 2.7%. No relationship was found between inadequate prophylaxis compliance and infection (RR: 1.01; 95% confidence interval: 0.95-1.11; p = 0.61).
Conclusions:
Compliance of antibiotic prophylaxis was high, but could be improved. No relationship was found between prophylaxis compliance and surgical site infection rate.
Palabras llave : Antibiotic prophylaxis; Compliance; Pediatrics; Surgical wound infection.