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Cirugía y cirujanos
versión On-line ISSN 2444-054Xversión impresa ISSN 0009-7411
Resumen
GUEVARA-NORIEGA, Kerbi A.; VILLAMIZAR, María Angelica; CASTRO-RIOS, Juan G. y POMAR, Jose L.. Outcomes of vascular allograft transplants in the autonomous community of Catalonia, Spain. Cir. cir. [online]. 2021, vol.89, n.6, pp.797-805. Epub 08-Feb-2022. ISSN 2444-054X. https://doi.org/10.24875/ciru.20001069.
Background:
The transplantation of tissues is a developing practice. Improving cryopreservation techniques and emerging of new immunobiology concepts have let to establish the transplant of vascular allografts as a suitable alternative. This study aims to expose the Catalan experience in vascular allograft transplantation by disclosing basic data about clinical outcomes.
Materials and Methods:
Data about vascular allografts transplants was gathered from the Registry of Vascular and Valvular Transplantation of Catalonia, Spain. Basic data regards to clinical outcomes are presented. Kaplan–Meier and statistical analysis were performed using SPSS Ver. 20 for Mac (Chicago USA).
Results:
One hundred and seventy-one adults were transplanted. The overall 5-year SR was 51.5%. Survival (SR) differs with the territory revascularized, ranging from 37.5% to 55.6% at five years. Major adverse limb event-free rate ranges from 13.3% to 50.1% according to the area treated. The Primary patency rate is higher in the supra-inguinal revascularization and lowers when a distal vessel target is treated.
Conclusion:
Only one guideline-supported indication is currently done for allografts, and our results match with this indication. Our results are extensive and susceptible to analysis to address future projects, which are required to reconsider new or specific indications. More studies are needed to clarify the outcomes of arterial allografts.
Palabras llave : Cryopreserved allografts; Major adverse limb event; Chronic limb-threatening ischemia; Vascular transplant; Vascular tissue.