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Gaceta médica de México
versión On-line ISSN 2696-1288versión impresa ISSN 0016-3813
Resumen
FADIL, Muhammad et al. Effect of remote ischemic postconditioning on left ventricular ejection fraction in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Gac. Méd. Méx [online]. 2023, vol.159, n.5, pp.434-438. Epub 20-Feb-2024. ISSN 2696-1288. https://doi.org/10.24875/gmm.m23000810.
Background:
Ischemic conditioning may help patients with ST-segment elevation myocardial infarction (STEMI) to limit ventricular remodeling.
Objectives:
To investigate the effect of remote ischemic postconditioning (RIPC) on left ventricular function during primary percutaneous coronary intervention (PPCI) in patients with STEMI.
Material and methods:
Pre- and post-test intervention study with a total of 60 STEMI patients. Patients were divided in two groups: with and without RIPC.
Results:
At 6-month follow-up evaluation, a significant difference in left ventricular ejection fraction was observed in patients who underwent PPCI, which was higher in the group with RIPC in comparison with the group without RIPC: 1.0 (−1.0 to 4.3) vs. −1.0 (−4.0 to 1.3), p = 0.033. In addition, at 6-month measurement, left ventricular end-systolic volume in patients without RIPC: was higher in comparison with their counterparts: 79.3 ± 30.5 mL versus 64.4 ± 21.4 mL, p = 0.032.
Conclusions:
RIPC shows favorable effects on left ventricular function and, therefore, in the future, it could be a potential cardioprotective strategy against ischemia-reperfusion injury in STEMI patients.
Palabras llave : Left ventricular ejection fraction; ST-segment elevation myocardial infarction; Remote ischemic postconditioning.