Resumen

VALENCIA SEGURA, Raida K.; COLIN BARENQUE, Laura  y  FORTOUL VAN DER GOES, Teresa I.. Dendritic spines, its function and some alterations. Rev. Fac. Med. (Méx.) [online]. 2018, vol.61, n.1, pp.46-55. ISSN 2448-4865.

The dendritic spines are dendritic membrane modifications rich in actin, whose morphology changes could suggest modifications in neural communication. These dendritic spines have a spiny-apparatus that regulates the intracellular calcium concentration. Recent reports mention the relationship between the number of spines and certain sleep disorders, the physiologic state in which memory consolidation takes place. Changes in their morphology and density are associated with several pathologies. In this revision we describe the morphological modifications of dendritic spines, their relationship with the development of the nervous system, sleep disorders and some other pathologies.

Palabras llave : Dendritic spines; sleep; neurodegeneration; memory.