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Revista de investigación clínica
versión On-line ISSN 2564-8896versión impresa ISSN 0034-8376
Resumen
NUNEZ, Isaac; BELAUNZARAN-ZAMUDIO, Pablo F. y CARO-VEGA, Yanink. Result Turnaround Time of RT-PCR for SARS-CoV-2 is the Main Cause of COVID-19 Diagnostic Delay: A Country-Wide Observational Study of Mexico and Colombia. Rev. invest. clín. [online]. 2022, vol.74, n.2, pp.71-80. Epub 02-Mayo-2022. ISSN 2564-8896. https://doi.org/10.24875/ric.21000542.
Background:
Delay in COVID-19 diagnosis due to late real-time reverse transcription-polymerase chain reaction reporting has been described to be an important cause of suboptimal COVID-19 surveillance and outbreak containment.
Objective:
The objective of the study was to determine the duration of diagnostic delay due to test turnaround time and its association with marginalization status.
Methods:
In this observational study using national open data of Mexico and Colombia, we quantified the delay in COVID-19 diagnosis that occurred in both countries. We considered two periods that contributed to the delay in diagnosis: the time from symptom onset until testing (delay-one) and test turnaround time (delay-two). Marginalization status was determined according to country-specific scores.
Results:
Among 3,696,773 patients from Mexico and Colombia, delay-two was generally longer than delay-one. Median delay-one was 3 days and delay-two 7 days in Colombia, while in Mexico, they were 3 days and 4 days, respectively. In Colombia, worse marginalization status prolonged delay-two. In Mexico, a lower number and percentage of rapid tests were performed in areas with worse marginalization.
Conclusion:
Diagnostic delay was mostly due to test turnaround time. Marginalization status was an important barrier to diagnostic test access.
Palabras llave : SARS-CoV-2; COVID-19; Real-time polymerase chain reaction; Mexico; Colombia.