Introduction:

teratomas are the most common extragonadal germ cell neoplasm in neonates, but they can have different locations. We describe the diagnostic-therapeutic process of three newborns with this type of tumor.

Cases presentation:

these are three neonates in whom, before birth, a tumor was detected by echocardiography in different locations: orbit, oropharynx, and sacrococcygeal. All three underwent surgical resection in the perinatal stage. By histopathology, the report was a mature teratoma. Alpha-fetoprotein and human chorionic gonadotropin levels confirmed the diagnosis. At the age of six months, the postoperative course has been satisfactory.

Conclusions:

identification of teratomas during gestation is important for management planning at birth. Complete surgical resection is the treatment of choice, and serum levels of tumor markers should be part of long-term surveillance.