Resumen

MIRANDA-AQUINO, T et al. Gastroesophageal junction small cell carcinoma. Med. interna Méx. [online]. 2017, vol.33, n.3, pp.403-406. ISSN 0186-4866.

Extrapulmonary small cell carcinomas (EPSCC) can arise in multiple organ sites and form a rare clinicopathological entity of high proliferative epithelial neuroendocrine tumors with aggressive biological behavior. Gastrointestinal is the most common source of EPSCC. We report a case of gastroesophageal junction small cell carcinoma, which was diagnosed in the context of upper gastrointestinal bleeding. A primary small cell lung carcinoma was excluded. Chemotherapy, neoadjuvant chemoradiotherapy and prophylactic cranial radiotherapy were given, with good clinical outcome. Our case of a very rare condition highlights the importance of recognizing atypical pathologic diagnoses. More research needs to be conducted with EPSCC patients in order to better characterize disease pathogenesis, and an optimal disease management.

Palabras llave : extrapulmonary small cell carcinomas; gastroesophageal junction small cell carcinomas; gastrointestinal small cell carcinomas; Azzopardi phenomenon; prophylactic cranial radiotherapy; cisplatin; etoposide.

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