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Medicina interna de México
versión impresa ISSN 0186-4866
Resumen
LENDECHY-VELAZQUEZ, Marysol y HERNANDEZ-DELGADO, Alejandra. IgG4-related disease. Med. interna Méx. [online]. 2019, vol.35, n.2, pp.313-320. Epub 30-Sep-2020. ISSN 0186-4866. https://doi.org/10.24245/mim.v35i2.2226.
This paper reports the case of two patients of 67 and 68 years old, both had a history of smoking and they started suffering with organomegaly and elevated serum globulins. The first patient presented parotidomegaly, xerostomia, xerophthalmia, recurrent uveitis and interstitial pneumonitis; a minor salivary gland biopsy was performed, which confirmed the diagnosis of systemic disease related to IgG4. The second patient presented a stony thyroid tumor, thyroidectomy was performed and the result of biopsy was Riedel’s thyroditis (organ-specific thyroid disease related to IgG4). The initial presentation of the disease by IgG4 can be very nonspecific. The manifestations presented by the patients can be confused with Sjögren’s syndrome or sarcoidosis (case 1) and with malignancy (case 2).
Palabras llave : IgG4; Riedel’s thyroiditis; Phlebitis; Sclerosis.