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Revista del Instituto Nacional de Enfermedades Respiratorias
versión impresa ISSN 0187-7585
Resumen
DURAN CRUZ, MAURICIO; LUJAN CASTILLA, POMPONIO JOSÉ y SANCHEZ MARIN, GABRIEL ALEJANDRO. AMILOIDOSIS LARÍNGEA. REPORTE DE UN CASO TRATADO EXITOSAMENTE CON RADIOTERAPIA EXTERNA. Rev. Inst. Nal. Enf. Resp. Mex. [online]. 2004, vol.17, n.3, pp.198-203. ISSN 0187-7585.
Laryngeal amyloidosis is an uncommon disease accounting for 0.68% of benign tumors of the larynx. It can present as a nodular tumor or diffuse subepithelial deposition forming a mass and causing hoarseness, dysphagia or even airway obstruction. Treatment has historically focused on debridement, laser ablation, stent placement and in some cases colchicine, melphalan and prednisone. We present a case of laryngeal amyloidosis persistent to management with laser ablation and melphalan/prednisone, successfully managed with external beam radiation therapy. Fourteen months after a moderate radiation dose, the patient remained without symptomatic or image data of disease. The literature concerning the role of radiation therapy in the treatment of laryngeal amyloidosis is reviewed.
Palabras llave : Amyloidosis; larynx; radiotherapy.