Resumen

OCELOTL PEREZ, Rafaelita et al. Central venous-arterial CO₂ difference as risk factor of death with septic shock. Rev. Asoc. Mex. Med. Crít. Ter. Intensiva [online]. 2016, vol.30, n.1, pp.30-42. ISSN 0187-8433.

Introduction: Severe sepsis and septic shock are a public health problem because of its high prevalence and mortality. The arteriovenous difference of CO₂ (ΔCO₂) under physiological conditions does not exceed more than 0.8 kPa (6 mmHg), reflecting adequate venous flow and cardiac output. A macrocirculatorio level there is an inverse relationship between ΔCO₂ and CI in critically ill patients. The aim of this study was to determine the risk of death in the short term ΔCO₂ more than 6 mmHg in patients with septic shock admitted to the intensive care service General Hospital "La Villa" Mexico City. Material and methods: Longitudinal and descriptive study. We included patients with septic shock at admission, without acute heart failure. Variables: delta CO₂; lactate, SvcO₂, sites of infection. We analyze the ΔCO₂ > 6 mmHg income at 6 and 12 hours. We obtained relative risk for short-term mortality. Results: They were 42 patients, 30 men and 12 women, mean age 39 years. Sites of infection: urinary in 18 patients, abdominal at 12, breathing at 6, and soft tissues 6. All patients who died had delta CO₂ > 6 mmHg at admission and at 6 hours and 20 patients at 12 hours. Conclusion: Relative risk of short-term death in patients with ΔCO₂> 6 mmHg is significantly increased when it remains high over time.

Palabras llave : ΔCO₂; delta CO₂; septic shock; venous-arterial CO₂ difference.