BACKGROUND:

It is well known that premature luteinization has a deletereous efecto on the outcome of IVF cycles however there are no reports that evaluate associated risk factor.

OBJECTIVE:

To evaluate factors associated to premature luteinization during folicular phase of IVF cycles under antagonist stimulation protocol.

MATERIAL AND METHODS:

This is a comparative, retrospective, observational study. 469 IVF flexible-antagonist protocol cycles were included from January 2009 to February 2014.

RESULTS:

We registered 469 IVF cycles. The IMC, basal estradiol, age and estradiol on trigger date showed correlation with premature luteinization. There were no association with basal FSH and LH nor total gonadotropin dose.

CONCLUSION:

Lowe age and IMC and higher estradio levels are associated to a higer level of progesterone on trigger date.