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Ginecología y obstetricia de México
versión impresa ISSN 0300-9041
Resumen
GUAJARDO-FLORES, Juan Pablo et al. What is the most significant cutting point of antimüllerian hormone as a predictor of the ovarian response, pregnancy rate and living born?. Ginecol. obstet. Méx. [online]. 2019, vol.87, n.6, pp.347-355. Epub 30-Jun-2021. ISSN 0300-9041. https://doi.org/10.24245/gom.v87i6.2564.
OBJECTIVE:
To evaluate the efficacy of antimülleriana hormone in prediction of the ovarian response, pregnancy rate and live birth.
MATERIALS AND METHODS:
In this retrospective, analytical and observational study, ovarian stimulation cycles were evaluated at the Hisparep Reproduction Center, in a period from January 1, 2010 to June 30, 2017, the inclusion criteria were; Age from 20 to 44 years and regular menstrual cycles. The exclusion criteria; altered male factor, altered uterine cavity, endocrine disorders, antecedent of ovarian damage. The study variables; antimüllerian hormone, oocytes recovered, mature, fertilized, embryos, pregnancy rate and live birth. The quantitative variables were analyzed by means of a comparison of means, using the Student's T test, the percentage variables by means of comparison of percentiles.
RESULTS:
223 cycles were evaluated, divided into groups using different cut points. It was determined that Antimullerian Hormone predicts a greater recovery of mature and fertilized oocytes using any cut point, we consider that 1.25 ng / mL was the most significant cutoff point, since it predicts higher embryo obtaining, relationship was observed in pregnancy rates clinical and live birth, although its predictive power is weak, however, using a cutoff of 0.5 ng / mL seems to predict low odds of live birth
CONCLUSIONS:
Antimullerian hormone is the best marker of ovarian response, we consider that 1.25 ng /mL is the most significant cut-off point, more studies are needed to evaluate its efficacy as a predictor of low rates of live birth.
Palabras llave : Pregnancy rate; Ovarian stimulation cycles; oocytes; Anti-Mullerian; Ovulation induction; Menstrual cycle; Live birth.