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Ginecología y obstetricia de México
versión impresa ISSN 0300-9041
Resumen
MARQUEZ-IBARRA, Adriana Alejandra; MARISCAL-RAMIREZ, Blanca Estela; GONZALEZ-PONCE, Ana María y VALBUENA-GREGORIO, Edith. Relationship between iron and gestational diabetes mellitus: a narrative review. Ginecol. obstet. Méx. [online]. 2022, vol.90, n.5, pp.434-442. Epub 12-Sep-2022. ISSN 0300-9041. https://doi.org/10.24245/gom.v90i5.7134.
OBJECTIVE:
To evaluate the scientific evidence about the relationship between iron and gestational diabetes mellitus.
METHODOLOGY:
Narrative review, based on the search for articles published from 2000 to 2021 in the PubMed, LILACS, BIREME, NICE, SIGN and CENETEC databases with the MeSH: Iron, iron and diabetes, Iron overland, Gestational Diabetes and Iron Overland and Gestational Diabetes. Those related to the topic of interest were selected.
RESULTS:
119 articles were found and only 34 were considered adequate for the purpose of the review because they were directly related to iron metabolism, gestational diabetes and iron as a cause of gestational diabetes. Cross-sectional studies, cases and controls, cohorts, trials, reviews and meta-analyses were obtained.
CONCLUSIONS:
The relationship between iron and gestational diabetes mellitus is not properly established; however, it has been related to the oxidative capacity of iron through different mechanisms that accentuate insulin resistance. It is suggested that high iron concentrations could be a risk factor for gestational diabetes mellitus.
Palabras llave : Iron; Gestational diabetes; Oxidative Stress; Insulin resistance; Risk factors.
