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Gaceta médica de México
versión On-line ISSN 2696-1288versión impresa ISSN 0016-3813
Resumen
SERRANO-BERRONES, Miguel Ángel y BARRAGAN-PADILLA, Sergio Baltazar. Estudio sobre la asociación de hipertrigliceridemia con los estados hipertensivos del embarazo. Gac. Méd. Méx [online]. 2019, vol.155, suppl.1, pp.27-31. Epub 01-Jul-2021. ISSN 2696-1288. https://doi.org/10.24875/gmm.19005137.
Background:
Preeclampsia occurs in 8% of pregnancies and generates 25% of perinatal deaths. Although its etiology is multifactorial, some metabolic alterations are associated with the endothelial dysfunction present in the disease, and its study could identify early markers of damage.
Objective:
To determine the relationship between plasma concentration of triglycerides in pregnant patients with hypertensive disease induced by pregnancy.
Methods:
Prospective study that included 147 healthy pregnant women and 120 women with hypertensive disease induced by pregnancy. Total cholesterol, low-density lipoprotein, high-density lipoprotein, Hemoglobin A1c, triglycerides, BH, QS, serum electrolytes, serum nitrites and liver function tests were determined.
Results:
A significant difference was found in the concentration of triglycerides between normotensive and patients with preeclampsia (261.22 ± 80.27 vs. 361.46 ± 135.17 mg/dl, p < 0.0008). In addition, a lower serum concentration of nitrites was observed in patients with preeclampsia, which helps explain vasoconstriction.
Conclusions:
We found an association between hypertriglyceridemia and the presence of diabetes mellitus II with the development of hypertensive disease induced by pregnancy.
Palabras llave : Hypertriglyceridemia; Preeclampsia; Pregnancy.