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Gaceta médica de México
versión On-line ISSN 2696-1288versión impresa ISSN 0016-3813
Resumen
GOMEZ-PINA, Juan J.; GONZALEZ-VEYRAND, Emma R. y LOPEZ ANGUIANO, Roberto R.. Clinical and radiological characteristics in patients with SARS-CoV-2-associated pneumonia. A descriptive study in a secondary care center. Gac. Méd. Méx [online]. 2021, vol.157, n.6, pp.594-599. Epub 13-Dic-2021. ISSN 2696-1288. https://doi.org/10.24875/gmm.21000182.
Introduction:
Real-time reverse-transcription polymerase chain reaction (RT-PCR) is the gold standard for establishing the diagnosis of coronavirus disease 2019 (COVID-19). Chest computed tomography (CCT), as a diagnostic complement, classifies tomographic findings according to the COVID-19 Reporting and Data System (CO-RADS).
Objective:
To determine CCT sensitivity and specificity for COVID-19 diagnosis.
Methods:
We reviewed RT-PCR results, as well as their respective CCTs. All CCTs were classified according to CO-RADS. CCT sensitivity and specificity were evaluated using the RT-PCR result that was closest to that of CCT as reference.
Results:
We included 412 patients, out of whom 277 were males (46-70 years) and 130 were females (45-71 years); with 181 negative and 231 positive tests, a sensitivity of 92.15 % and specificity of 79.32 % were obtained. Mortality increased after six hospitalization days, in males and in CO-RADS 4, 5 and 6 in comparison with CO-RADS 1, 2 and 3.
Conclusions:
Early diagnosis play a decisive role in prognosis of SARS CoV 2 pneumonia; although RT-CPR is the current gold standard, false negatives are common findings, reason why chest CT help to confirm suspected cases, even in early stages. This image study is accessible and a fast tool. Therefore, CT most be considered as an essential study to be done in all suspected COVID 19 patients, classifying into the CO-RADS system classification, as a diagnosis and prognostic tool.
Palabras llave : CO-RADS; Clinical; Radiological; Characteristics; SARS-CoV-2.