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Revista mexicana de pediatría
versión impresa ISSN 0035-0052
Resumen
CALVA-RODRIGUEZ, Roberto et al. Hepatitis B antibody levels in adolescents: comparison of children vaccinated at birth versus vaccinated at 12 months of age. Rev. mex. pediatr. [online]. 2022, vol.89, n.1, pp.36-39. Epub 03-Jun-2024. ISSN 0035-0052. https://doi.org/10.35366/106859.
Objective:
To compare the levels of protective antibodies against hepatitis B virus in 14-year-old patients, between those vaccinated at birth and those vaccinated at one year of age.
Material and methods:
Cross-sectional study with 62 healthy patients. Hepatitis B surface antigen (anti-HBs) antibody levels were measured; values > 10 IU/mL were considered protective.
Results:
Of the total, 40 patients (64.5%) were vaccinated at birth and 22 (35.5%) at one year of age. Serum levels in the latter group were statistically higher, with no difference by sex. Twenty-four patients (38.7%) achieved protective levels, eight (33.3%) from the group vaccinated at birth, and 16 (66.6%) from the other group.
Conclusions:
Vaccination against hepatitis B at one year of age seems to generate a greater probability of obtaining protective antibody titers at the age of 14 years.
Palabras llave : immunization; hepatitis B; antibodies; adolescents.
