OBJECTIVE:

To analyze the incidence, risk factors and perinatal outcomes of patients with thrombophilia and pregnancy.

MATERIALS AND METHODS:

Observational study of a series of cases at the General Hospital Fernando Quiroz Gutiérrez ISSSTE. From 2010 to 2016. We included all pregnant women with a diagnosis of thrombophilia, performed with a thrombophilia profile. Treatment with acetylsalicylic acid and low molecular weight heparin was started since diagnosis. Pregnancy and puerperium surveillance was performed with observation of results, which were captured and analyzed with the Excel program.

RESULTS:

There were 81 cases, with an incidence of 1.06%. The most frequent thrombophilia was the antiphospholipid antibody syndrome 39.5%, followed by the protein S deficiency 35.8%. The most frequent risk factors were: recurrent gestational loss 63%, preeclampsia 23% and fetal death 17%. Perinatal outcomes after treatment: 97.6% of healthy neonates, 2.4% of abortions and 4.9% of preeclampsia.

CONCLUSIONS:

A history of repeated gestational loss, fetal growth restriction, hypertensive pregnancy and fetal death should lead to suspected thrombophilia; With the obligation to carry out study protocol for confirmation. Reproductive success is feasible, if the binomial is subjected to strict monitoring and timely treatment.