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Ginecología y obstetricia de México
versión impresa ISSN 0300-9041
Resumen
CARRANZA-LIRA, Sebastián y CARPIO-BARCENAS, Paulina. Time since menopause and its effect on cognitive deterioration. Ginecol. obstet. Méx. [online]. 2018, vol.86, n.5, pp.289-296. ISSN 0300-9041. https://doi.org/10.24245/gom.v86i5.1820.
OBJECTIVE
To determine if the time since menopause has effect on cognitive status and if hormone therapy (HT) influences it.
MATERIALS AND METHODS
Observational, cross-sectional, prospective, comparative, open study in which postmenopausal women were evaluated with the Mental Mini State Examination (MMSE) and the Menopause Rating Scale (MRS). The differences were analyzed according to time since menopause among those that received or non-HT. Student t test and Pearson’s correlation analysis were done.
RESULTS
Ninety-four women were studied and divided in two groups: Group I, with HT (n =46) and Group II, without HT (n =48). The MMSE score was greater in group I, also space orientation, differed memory and language scores were greater in the group with 10 or less years since menopause when comparing it with those with more than 10 and up to 20 years and similar happened with the MRS score. In group II, the score in temporary orientation was greater in the group with 10 or less years, when compared with that with more than 10 and up to 20 years group; and with the group with more than 20 years similar happened for fixation-memory, calculation, language and MMSE score. In group I correlation was found between MMSE score and age -0.746, p < 0.001 and time since menopause -0.722, p < 0.001. In group II it was between MMSE score and age -0.863, p < 0.001 and time since menopause -0.873, p < 0.001.
CONCLUSION
Age negatively influenced the cognitive function, but this was greater in the group without HT.
Palabras llave : Menopause; Cognitive function; Space orientation; Memory; Language; Hormonal therapy.