Objective:

Look for the effect that academic stress has on the cognitive processes of sixth-year students belonging to the Military School of Medicine during their undergraduate internship.

Materials and methods:

The research process was carried out in three phases, where the obtaining of measurements of the P300 wave and the evaluation of academic stress in pre-guard and post-guard cover the first two phases and the collection and comparison of the data obtained in phases one and two consisted of the last phase.

Results:

When obtaining the mean latency of the P300 wave pre-guard 286.36 ms and at the rear of 331.98, a prolongation in said parameter was identified, with a p=<0.0001, highly significant. Regarding the amplitude of the wave in the pre-guard, an average of 13,050 µV was obtained and in post-guard of 7,784 µV. A directly proportional association was found between the stress test score obtained in the foreguard and the P300 latency obtained at the same time, when using the Spearman correlation (r=0.996, p=<0.001). The comparison revealed an inversely proportional association (r=0.998, p=<0.001). There was an inversely proportional relationship between the amplitude of P300 obtained in the rearguard and the stress test score obtained in the rearguard (r=0.998, p=0.001). With these results we can affirm the association of the morphological changes of P300 with the scores obtained in the applied stress tests.