Objective:

Jaw osteosarcoma shows a variety of histomorphological clinical conditions. Despite the advances in molecular pathogenesis and biological markers, clinicopathological correlation is considered the most important criterion in diagnosis.

Material and methods:

The database of the Surgical Pathological Department of the General Hospital of Mexico was reviewed to obtain cases of osteosarcoma during the period from 2002 to 2019. The cases were evaluated on the Enneking scale, which has prognostic considerations.

Results:

Regarding the 11 cases found, 54.5% are women. The average age was 36 years old, the primary location was the jaw. The average size was 8 cm. Clinicopathological concordance was 27.3%. The most frequent histologic variant was chondroblastic. The predominant histological grade was high and 83% of the cases had surgical margins involved.

Conclusion:

The patients were in the fourth decade of their life, the tumors were large in size with a high histological grade of malignity and the majority of cases had affected surgical margins. All data had a bad prognostic.

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