Resumen

MORALES-NAVA, Rosmarbel  y  OLIVO, Horacio F.. Synthetic Applications of Sulfur-based Chiral Auxiliaries in Asymmetric Syntheses. J. Mex. Chem. Soc [online]. 2019, vol.63, n.3, pp.93-104.  Epub 14-Sep-2020. ISSN 1870-249X.  https://doi.org/10.29356/jmcs.v63i3.527.

This mini-review intends to present one of the themes that has driven my research in developing methodology for the synthesis of natural products and important biologically active molecules. Sulfur-based chiral auxiliaries from aminoacids have been shown to have superior qualities in many cases to other well-known chiral auxiliaries. Some applications of these auxiliaries include acetate aldol reactions, resolution of racemic mixtures, Michael additions, intramolecular thio-Michael/aldol cyclization cascade reactions, and synthesis of natural products, including a new practical and efficient indene-based thiazolidinethione auxiliary.

Palabras llave : thiazolidinethione; oxazolidinethione; chiral auxiliary; aldol reaction; natural products..