Resumen

GARCIA-ARGAEZ, Aída N.; GONZALEZ-LUGO, Nadia M.; MARQUEZ, Carmen  y  MARTINEZ-VAZQUE, Mariano. Cumarinas presentes en especies del género Casimiroa. Rev. Soc. Quím. Méx [online]. 2003, vol.47, n.2, pp.151-154. ISSN 0583-7693.

Leaf and seeds extracts of Casimiroa pubescens, C. edulis and C. calderoniae were analyzed by HPLC. The results showed that coumarins phellopterin (6), isopimpinellin (9), heraclenol (15) and heraclenin (16) were present in all species studied. Of all species, C. calderoniae showed the highest concentration of this type of metabolites. These results, in addition to those previously reported, indicate that 16 different coumarins occur in the genus. Even though it has been proposed that the umbelliferone is a common precursor in the biogenesis of the Casimiroa coumarins, there is a clear difference between the coumarins synthesized by C. greggii and those present in the rest of the species. Thus, seselin and O-geranylosthenol, both synthesized from an umbelliferone prenylated at C-8, are present in C. greggii, while the coumarins present in the other species originate from umbelliferone prenylated at C-6.

Palabras llave : Casimiroa; coumarins; Rutaceae; umbelliferone.