Resumo

CEDILLO-ALVAREZ, Carla et al. COVID-19: a basic approach to understanding potential treatments. Gac. Méd. Méx [online]. 2020, vol.156, n.6, pp.580-585.  Epub 27-Maio-2021. ISSN 2696-1288.  https://doi.org/10.24875/gmm.20000452.

SARS-CoV-2 virus has been identified as the causative agent of the COVID-19 pandemic. Even when no standard treatment is available, antivirals such as remdesivir and other drugs such as chloroquine and ivermectin, which interfere with viral replication, have been assayed. Some strategies aimed to reduce immune mechanisms, such as the use of tocilizumab and natural antioxidants, have also been tested. The use of drugs related to the renin-angiotensin system has been controversial. Pathogenicity mechanisms, as well as controlled treatments, still have to be studied in detail in order to propose a viable therapeutic option that prevents the entry and replication of the virus or enhances the host immune system.

Palavras-chave : Covid-19; Pharmacological treatments; Renin-angiotensin system.