Resumo

DAVILA DUPONT, David  e  PENA LOPEZ, Idelfonso Roberto de la. Hemophagocytic syndrome. Case report and review of the literature. Rev. Fac. Med. (Méx.) [online]. 2019, vol.62, n.2, pp.15-21.  Epub 16-Out-2020. ISSN 2448-4865.  https://doi.org/10.22201/fm.24484865e.2019.62.2.04.

Hemophagocytic syndrome is a disease characterized by fever, cytopenia, splenomegaly and other alterations in laboratories due to excessive activation of macrophages, by genetic mutations or secondary to infections, malignancy or rheumatological diseases.

Because of the low specificity of the symptoms, the diagnosis is usually late. Its management requires the treatment of the underlying cause and, if necessary, medications that decrease the inflammatory response.

Palavras-chave : Hemophagocytic syndrome; fever; hemophagocytosis.