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Medicina interna de México
versão impressa ISSN 0186-4866
Resumo
REBOLLEDO-GARCIA, D; GONZALEZ-VARGAS, PO e SALGADO-CALDERON, I. Guillain-Barre syndrome: older and news concepts. Med. interna Méx. [online]. 2018, vol.34, n.1, pp.72-81. ISSN 0186-4866. https://doi.org/10.24245/mim.v34i1.1922.
Currently, Guillain-Barre syndrome (GBS) is the most frequent cause of acute flaccid paralysis. The classical form of syndrome has not undergone major changes in their clinical behavior; however, the spectrum of clinical variants of the syndrome is extensive, supporting advances in molecular biology and immunology have allowed better characterize these forms of GBS. The anti-ganglioside antibodies have restructured the criteria because they increase the sensitivity and specificity of diagnosis; because of this, the traditional criteria are inadequate for appropriated classification and discriminate imitators of the syndrome. The evolution of the criteria should change the perspective in addressing the box and regulate the therapeutic approach, without exceeding the clinical trial of daily medical practice.
Palavras-chave : Guillain-Barre syndrome; Antibodies.