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Ginecología y obstetricia de México

versão impressa ISSN 0300-9041

Resumo

MONTANO-SERRANO, María et al. Treatment of breast cancer in pregnant women: clinical case. Ginecol. obstet. Méx. [online]. 2019, vol.87, n.5, pp.324-333.  Epub 30-Jun-2021. ISSN 0300-9041.  https://doi.org/10.24245/gom.v87i5.2811.

BACKGROUND:

Breast cancer is the most prevalent cancer nowadays and is the most common at the pregnancy and postpartum period. The incidence is between 0.2-2.6% and is currently increasing due to delayed childbearing. The treatment implies a challenge for the health systems because the welfare of the mother and her child must be valued and safeguarded.

CLINICAL CASE:

A 26-year-old patient who attended the consultation for right mastalgia, with rapid growth from the beginning of pregnancy. During the mammary examination, a hard consistency tumor of 8 cm was observed, occupying both upper quadrants of the right breast, with reddening of the skin. The ultrasound revealed a heterogeneous solid-cystic tumor, 8 x 5 cm, without pathological axillary lymph nodes. The anatomopathological study of the biopsy reported an infiltrating carcinoma, with triple negative immunophenotype (negative immunoreactivity for estrogen and progesterone receptors, and Her-2 with Ki67 proliferation index of 80%), which confirmed the diagnosis of breast cancer locally advanced in the second trimester of pregnancy. After administration of three cycles of neoadjuvant chemotherapy with anthracyclines (doxorubicin and cyclophosphamide) trisemanales, termination of pregnancy was indicated by induction of labor at week 36 + 6. A male was born at 2800 g, with Apgar 9-10- 10 The mother and her son evolved satisfactorily, so they were discharged 4 days after the intervention. Ten months after mastectomy, she enjoys good physical and psycho-logical health, as does her 15-month-old son. Continues in close monitoring in the Oncology service.

CONCLUSIONS:

The treatment of breast cancer during pregnancy is safe and offers good long-term results. The important intervention and multidisciplinary assessment, in addition to the correct advice and psychological support to the family.

Palavras-chave : Breast cancer; Pregnancy; Radiotherapy; Chemotherapy; Sentinel lymph node biopsy; Mastectomy.

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