Resumo

CABEZAS, Fabio et al. Análisis del contenido alcaloidico de Caliphruria Subdentata Baker (Amaryllidaceae) por el método CG-EM. Rev. latinoam. quím [online]. 2013, vol.41, n.1, pp.68-73. ISSN 0370-5943.

Caliphruria is a genus of bulbous plants in the Amaryllidaceae family. It consists of four species distributed in tropical regions of South America, three of them are endemic of Colombia. This genus is infrequent in nature, with restricted geographical distribution. C. subedentata Baker is threatened by extinction. The polar extract showed moderate cytotoxic activity. In previews phytochemical studies, by classical methods, we isolated six alkaloids: galanthamine, lycorine, haemantamine, maritidine, homolycorine and hamayna. In this work we reports 18 compounds identified by GC-MS technique: ismine, trisphaeridine, 5,6-dihydrobicolorine, galanthamine, clidantine, narwedine, kirkine, galantindol, maritidine, anhydrolycorine, deoxytazetine, 6-methoxypretazzetine, tazzetine, haemantamine, 11,12-de-hydroanhydrolycorine, lycorine, homolycorine, epimacronine and one alkaloid not identified.

Palavras-chave : Alkaloids; galanthamine; lycorine; Caliphruria subedentata; Amaryllidaceae; GC-EM method; biological activity.