Resumo

GONZALEZ PACHECO, Héctor. From thrombin hypothesis to inflammation: It is reality?. Arch. Cardiol. Méx. [online]. 2006, vol.76, suppl.2, pp.233-238. ISSN 1665-1731.

The classical pathophysiologic concept of the acute coronary syndromes is the coronary artery thrombosis as a consequence of rupture or vulnerable atherosclerotic plaques. Actually, it is also been considered that systemic inflammatory phenomenon play a central role in the plaque instability associated to the atherothrombotic activity of the tissue factor (TF). The throm-botic phenomenon is controlled by tissue factor, stimulating the way of the protease's active receptors (PAR) and cause a negative cycle between inflammation and coagulation.

Palavras-chave : Acute coronary syndrome; Inflammation; Thrombin.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )