Serviços Personalizados
Journal
Artigo
Indicadores
- Citado por SciELO
- Acessos
Links relacionados
- Similares em SciELO
Compartilhar
Journal of the Mexican Chemical Society
versão impressa ISSN 1870-249X
Resumo
TIBHE, Gaurao D.; REYES-GONZALEZ, Miguel Ángel; CATIVIELA, Carlos e ORDONEZ, Mario. Microwave-assisted High Diastereoselective Synthesis of α -Aminophosphonates under Solvent and Catalyst Free-conditions. J. Mex. Chem. Soc [online]. 2012, vol.56, n.2, pp.183-187. ISSN 1870-249X.
A simple, efficient and general method has been developed for the high diastereoselective synthesis of α-aminophospho-nates through "one-pot" three-component reaction of alkyl and aryl aldehydes with (S)-α-methylbenzylamine or (S)-3,3-dimethyl-2-butylamine and dimethyl phosphite (Kabachnik-Fields reaction), which proceeds in short time using microwave irradiation under solvent and catalyst free-conditions. This method could be useful in the large-scale synthesis of α-aminophosphonates in short reaction time.
Palavras-chave : Three-component Reaction; Diastereoselective Synthesis; α-aminophosphonates; Aicrowave; Green-Chemistry.