Background:

Sjögren syndrome is a chronic, autoimmune, inflammatory diseases characterized by diminished lacrimal and salivary gland function, although the clinical manifestations of SS include both exocrine gland involvement and extraglandular disease features.

Clinical case:

A 37-year-old female with xerosis, xerophthalmia, xerostomia, vulvovaginal dryness, fatigue and mild sensory neuropathy since 8 months ago. Physical examination: bilateral parotid gland enlargement. She was hospitalized and presented positive Schirmer test, positive salivary scintigraphy, and magnetic resonance with features typical of Sjögren disease; laboratory showed IgG type 1, 19350.0 mg/L; antibodies: anti SSA/Ro, 179.66; AC SSB/La, 114.01, and antinuclear antibodies with speckled pattern reaction 1:5120. After diagnosis, hydroxychloroquine and treatments for dry eye and dry mouth were prescribed.

Conclusion:

A patient with primary Sjögren’s syndrome and mild extraglandular organ involvement, like sensory neuropathy, without important systemic repercussion.